CRC Press Monographs in Contact Allergy, Volume 1: Non-Fragrance Allergens in Cosmetics (Part 1 and Part 2)

Monographs in Contact Allergy, Volume 1: Non-Fragrance Allergens in Cosmetics (Part 1 and Part 2) is the first 2-part volume in an exciting series on contact allergy.It presents over 500 natural or synthetic chemicals and compounds which have caused allergic contact dermatitis in cosmetic products. Included here are INCI names, synonyms, description/definition, CAS and EU numbers, chemical class, function in cosmetics, molecular formula, structural formula and advice on patch tests. A full literature review is given of patch testing in patients, case reports of cosmetic allergic contact dermatitis, irritant contact dermatitis, photosensitivity, immediate contact reactions and systemic side effects. This text is suitable for anyone with an interest in contact allergy, from university students to professionals, and all readers will find this informative and detailed series an invaluable resource.Key Features:Monographs of all known non-fragrance chemicals and substances which have caused allergic contact dermatitis from their presence in cosmetic productsProvides lists of all functional groups (such as antioxidants, preservatives, artificial nail building, emollients, hair dyeing, hair colorants) in both the EU and US formats and all chemicals in these groups which have caused cosmetic allergyPresents an alphabetical list of all synonyms indicating their INCI namesReported cross-reactions, pseudo-cross-reactions and co-reactions, patch test sensitization and presence in cosmetic products (including data from FDA’s Voluntary Cosmetic Registration Program) and chemical analyses are discussedCovers an extensive amount of information to benefit dermatologists, allergists, and non-medical professionals involved with the research, development and marketing of cosmetic products Review 'Anton de Groot has outdone himself!In Monographs in Contact Allergy, he has provided a 2 volume-catalog of close to 500 non-fragrance chemicals in cosmetics that span the common and the rare.This authoritative compendium will be a useful resource for those of us -- academicians, practitioners, industry professionals -- who manage, study, and think about individuals with contact dermatitis.'– Ponciano D. Cruz, Jr., MD, Editor-in-Chief, Dermatitis ‘This two-part 1430 pages book written by Anton de Groot presents 500 monographs on chemicals and substances that have caused contact allergy / allergic contact dermatitis by their presence in cosmetics. Each monograph begins with the section "Identification": name, description/definition, chemical class, IUPAC name, other names, CIR and SCCS data, functions in cosmetics, patch testing advice, chemical formula and (beautifully drawn) structural formulas. In each monograph, data are provided (if such information is available) on results of patch testing in unselected patients suspected of contact dermatitis (routine testing), testing in selected patient groups (e.g., individuals suspected of cosmetic reactions, patients with leg ulcers, hairdressers, children, patients with periorbital dermatitis), case reports and case series of cosmetic allergy, allergy from non-cosmetic products, cross-reactivity, patch test sensitization, provocation tests, dilution series testing, chemical analyses and frequency of use in cosmetics in the USA (including recent data from FDA’s Voluntary Cosmetic Registration Program). Next, info is provided on irritant contact dermatitis, immediate contact reactions, non-eczematous adverse effects, systemic side effects and other relevant data. In other words, the monographs are not limited to cosmetic allergy but provide full reviews. Many are 1-3 pages only, but some monographs have >10 pages (e.g.,benzophenone-3, chlorhexidine digluconate, imidazolidinyl urea, propylene glycol), >20 (colophonium, formaldehyde, methylisothiazolinone) and even >30 pages (MCI/MI and p-phenylenediamine).Because of our special interest in p-phenylenediamine, I have studied this