Humana Molecular and Cellular Pediatric Endocrinology: 10 (Contemporary Endocrinology, 10)

Stuart Handwerger, MD and a distinguished panel of clinicians and experts review the most significant recent developments in molecular and cellular biology, powerful advances that have produced new diagnostic methods and improved treatments for many pediatric endocrine diseases. Topics range from the growth hormone/prolactin/placental lactogen gene family and their regulation of growth, to steroid hormones, sexual development, and mineral corticoid action. Additional chapters examine the pathophysiology of insulin-dependent diabetes mellitus, the molecular genetics of thyroid cancer, the molecular basis of hypophosphatemic rickets, and inherited diabetes insipidus. Molecular and Cellular Pediatric Endocrinology offers today's clinicians and researchers not only the latest findings on endocrine diseases in their pediatric manifestations, but also highly practical insights into today's cutting-edge diagnostics, treatment strategies, and powerful new therapeutics. Review ". . . overview[s] the most rapidly developing areas of advances in molecular advances and their applications to the study, diagnosis, and treatment of pediatric endocrine disorders. The first seven chapters focus on the regulation of growth and the growth hormone/prolactin/placental lactogen gene family. Steroid hormones, sexual development, and mineralacortoid action are discussed in the next five chapters (including a review of the first human case of estrogen receptor defects). The pathophysiology of diabetes mellitus is the subject of two chapters. The rest of the text treats the molecular genetics of thyroid cancer, hypophosphatemic rickets, and inherited diabetes insipidus."-SciTech Book News ". . .cuts a wide and deep swath through the basic biology and pathology of the disorders [pediatric endocrinologists] deal with in the clinic every day. No matter your disease(s) of interest, its molecular/cellular basis is covered in this mutiauthored book. . . well referenced."-PedEndoGram "A useful addition to clinical pediatric endocrinology and of interest also to geneticists."-Journal of Pediatric Endocrinology and Metabolism From the Back Cover In Molecular and Cellular Pediatric Endocrinology, Stuart Handwerger, MD and a distinguished panel of clinicians and experts review the most significant recent developments in molecular and cellular biology, powerful advances that have produced new diagnostic methods and improved treatments for many pediatric endocrine diseases. Topics range from the growth hormone/prolactin/placental lactogen gene family and their regulation of growth, to steroid hormones, sexual development, and mineral corticoid action. Additional chapters examine the pathophysiology of insulin-dependent diabetes mellitus, the molecular genetics of thyroid cancer, the molecular basis of hypophosphatemic rickets, and inherited diabetes insipidus. Molecular and Cellular Pediatric Endocrinology offers today's clinicians and researchers not only the latest findings on endocrine disorders in their pediatric manifestations, but also highly practical insights into today's cutting-edge diagnostics, emerging treatment strategies, and powerful new therapeutics.