F A Davis Co Molecular Diagnostics

The first text on molecular diagnostics specifically designed to educate students in clinical laboratory science programs! The authors have combined their knowledge and experience as educators to bring you the book you and your students have been asking for. This exceptional new resource introduces the fundamentals of nucleic acid biochemistry to students without previous molecular training, while also presenting advanced concepts for students learning at a higher level. And, your students will be better prepared for the future with discussions of general diagnostic procedures that emphasize the continuing emergence of new diagnostic technologies. KEY FEATURES The application of molecular diagnostics to the clinical laboratory encompasses microbiology, virology, genetics, oncology, and human identification. Objectives guide the reader toward the knowledge that should be gained upon completion of each chapter. Advanced Concepts appear in boxes throughout the text to challenge those students interested in a higher level of learning. Historical Highlights enable interested students to apply a historical perspective to the topics. Case Studies in the clinical chapters show students how to apply molecular concepts to diagnostic testing. Key Terms are bolded and defined within the text where they first appear. Study Questions at the end of each chapter reinforce the content. Answers, included in the appendix, allow for self assessment outside of the classroom. Citations of seminal publications encourage the interested student to read and pursue at greater depth the various topics discussed CONTENTS I. Fundamentals of Nucleic Acid Biochemistry: An Overview DNA RNA Proteins II. Common Techniques in Molecular Biology Nucleic Acid Extraction Methods Resolution and Detection of Nucleic Acids Analysis and Characterization of Nucleic Acids and Proteins Nucleic Acid Amplification Chromosomal Structure and Chromosomal Mutations Gene Mutations DNA Sequencing III. Techniques in the Clinical Lab DNA Polymorphisms and Human Identification Detection and Identification of Microorganisms Molecular Detection of Inherited Diseases Molecular Oncology DNA-Based Tissue Typing Quality Assurance and Quality Control in the Molcular Laboratory Appendix Index