Wiley Applied Optimal Designs

There is an increasing need to rein in the cost of scientific study without sacrificing accuracy in statistical inference. Optimal design is the judicious allocation of resources to achieve the objectives of studies using minimal cost via careful statistical planning. Researchers and practitioners in various fields of applied science are now beginning to recognize the advantages and potential of optimal experimental design. Applied Optimal Designs is the first book to catalogue the application of optimal design to real problems, documenting its widespread use across disciplines as diverse as drug development, education and ground water modelling. Includes contributions covering:Bayesian design for measuring cerebral blood-flowOptimal designs for biological modelsComputer adaptive testingGround water modellingEpidemiological studies and pharmacological modelsApplied Optimal Designs bridges the gap between theory and practice, drawing together a selection of incisive articles from reputed collaborators. Broad in scope and inter-disciplinary in appeal, this book highlights the variety of opportunities available through the use of optimal design. The wide range of applications presented here should appeal to statisticians working with optimal designs, and to practitioners new to the theory and concepts involved. Review "The wide range of analytical concepts and applications focused upon here will attract statisticians interested in design theory and researchers in many of the fields in which it is used." (Journal of the American Statistical Association, March 2006) From the Inside Flap There is an increasing need to rein in the cost of scientific study without sacrificing accuracy in statistical inference. Optimal design is the judicious allocation of resources to achieve the objectives of studies using minimal cost via careful statistical planning. Researchers and practitioners in various fields of applied science are now beginning to recognize the advantages and potential of optimal experimental design. Applied Optimal Designs is the first book to catalogue the application of optimal design to real problems, documenting its widespread use across disciplines as diverse as drug development, education and ground water modelling. Includes contributions covering:Bayesian design for measuring cerebral blood-flowOptimal designs for biological modelsComputer adaptive testingGround water modellingEpidemiological studies and pharmacological modelsApplied Optimal Designs bridges the gap between theory and practice, drawing together a selection of incisive articles from reputed collaborators. Broad in scope and inter-disciplinary in appeal, this book highlights the variety of opportunities available through the use of optimal design. The wide range of applications presented here should appeal to statisticians working with optimal designs, and to practitioners new to the theory and concepts involved. From the Back Cover There is an increasing need to rein in the cost of scientific study without sacrificing accuracy in statistical inference. Optimal design is the judicious allocation of resources to achieve the objectives of studies using minimal cost via careful statistical planning. Researchers and practitioners in various fields of applied science are now beginning to recognize the advantages and potential of optimal experimental design. Applied Optimal Designs is the first book to catalogue the application of optimal design to real problems, documenting its widespread use across disciplines as diverse as drug development, education and ground water modelling. Includes contributions covering:Bayesian design for measuring cerebral blood-flowOptimal designs for biological modelsComputer adaptive testingGround water modellingEpidemiological studies and pharmacological modelsApplied Optimal Designs bridges the gap between theory and practice, drawing together a selection of incisive articl