Wiley Chemical Synthesis of Hormones, Pheromones and Other Bioregulators (Postgraduate Chemistry)

Many small molecules occur naturally as "messenger" chemicals which regulate the behaviour and functions of microbes, plants, insects and animals. Examples include hormones, pheromones, phytoalexins, and antifeedants. These biofunctional molecules are of great interest to researchers in helping develop our understanding of biological function and in the development of new drugs. However extracting them from nature can be prohibitively expensive, so there is great interest in devising methods of synthesising them from simple starting materials in the laboratory. Chemical Synthesis of Hormones, Pheromones and Other Bioregulators is an introduction to the techniques and strategies for the synthesis of biofunctional small molecules. Topics include:what are biofunctional molecules?why must biofunctional molecules be synthesized?how can we synthesize biofunctional molecules?the synthesis of phytohormones, phytoalexins and other biofunctional molecules of plant originthe synthesis of insect juvenile hormones and antifeedantsthe synthesis of pheromones and the significance of chirality in pheromone sciencethe synthesis of microbial hormones and pheromones, antibiotics, and other biofunctional molecules of microbial originthe synthesis of marine antifeedants and medicinal candidatesa synthetic examination of incorrectly proposed structures of biomoleculesreflections on science as a human endeavorDrawing on a career of almost 50 years researching and teaching this subject, Kenji Mori's Chemical Synthesis of Hormones, Pheromones and Other Bioregulators is a must-have textbook for students and researchers of organic synthesis and natural products, and a stimulating and inspiring account of a distinguished chemical career. Review "This volume will reward the attention of anyone interested in organic synthesis, in natural products chemistry, or in chemical ecology. It should inspire more synthetic organic chemists to pay attention to current research on the roles played by small molecules in the lives of organisms, and it should encourage biologists and structural chemists to identify, contact, and collaborate with chemical colleagues who are mentally and physically equipped to carry out stereospecific syntheses of nature's signal molecules." (Journal of the American Chemical Society, 23 February 2011) From the Inside Flap Many small molecules occur naturally as 'messenger' chemicals which regulate the behaviour and functions of microbes, plants, insects and animals. Examples include hormones, pheromones, phytoalexins, and antifeedants. These biofunctional molecules are of great interest to researchers as they help to increase our understanding of biological functions and they are useful in the development of new drugs. However, extracting them from nature can be expensive so there is great interest in devising methods of synthesizing them from simple starting materials in a laboratory. Chemical Synthesis of Hormones, Pheromones and Other Bioregulators is an introduction to techniques and strategies for the synthesis of biofunctional small molecules. Topics include:biofunctional molecules and organic synthesissynthesis of phytohormones, phytoalexins and other biofunctional molecules of plant originsynthesis of insect bioregulators other than pheromonessynthesis of pheromonessynthesis of biofunctional molecules of microbial originsynthesis of marine bioregulators, medicinals and related compoundssynthetic examination of incorrectly proposed structures of biomoleculesconclusion — science as a human endeavourDrawing on a career of almost 50 years of researching and teaching this subject, Kenji Mori's Chemical Synthesis of Hormones, Pheromones and Other Bioregulators is a must-have textbook for students and researchers of organic synthesis and natural products, and a stimulating and inspiring account of a distinguished career in chemicals. From the Back Cover Many small molecules occur nat