Progress in Medicinal Chemistry (Volume 39) - Image 1

£79.01

Elsevier Progress in Medicinal Chemistry (Volume 39)

Name: Progress in Medicinal Chemistry (Volume 39)
Brand: Elsevier
Price: 79.01 GBP
Availability: InStock

Laboratory Medicine

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Description

This volume covers contemporary advances in five important areas of pharmacology and medicinal chemistry including: a comprehensive account of inhibitors of the caspase family of proteolytic enzymes that represent a new class of anti-inflammatory and antiapoptotic agents of potential value in rheumatoid arthritis, and other peripheral and central indications; adoc umented survey of semi-synthetic and totally synthetic antibiotics and anti HIV agents and their sites of interaction; inhibitors of the intracellular enzyme acyl-CoA: cholesterol O-acyltransferase (ACAT) developed for the treatment of hypercholesterolemia; and recent progress in growth hormone secretagogues, with the focus on strategies to improve oral bioavailability and duration of action. Inhibition of the proteolytic enzyme, hepatitis C protease N-3(NS3), required for viral replication, is one of the most attractive targets for HCV infections. Progress and prospects in the design of peptide and non-peptide inhibitors are described here. design and clinical potential of new drug molecules; valuable summaries of structure-activity relationships in topical areas of medicinal chemistry; and extensive references to the biology, medicinal chemistry and clinical aspects of each topic.

Product Specifications

Brand: Elsevier
Format: hardcover
ASIN: 0444509593
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Allied Health Professions > Laboratory Medicine
Domain: Amazon UK
Release Date: 28 April 2002
Listed Since: 09 February 2007

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Elsevier Progress in Medicinal Chemistry (Volume 39)

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