£225.89

About as cheap as it gets — within 5% of the all-time low it hit 3 months ago.

£226 today · all-time low £225 (Aug 2026) · usually £258

Elsevier Nonclinical Evaluation Studies of Cellular and Gene Therapy Products: Strategies, Models, and Regulatory Frameworks

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£260.99 £220.93 £229.67 £238.41 £247.15 £255.89 £264.63 11 August 2026 29 August 2026 16 September 2026 04 October 2026 23 October 2026
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42 days 1 day · current 31 days 0 11 21 32 42 £225 £226 £261 Days at Price

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Most common price: £225 (42 days, 56.8%)

Price range: £225 - £261

Price levels: 3 different prices over 74 days

Description

Nonclinical Evaluation Studies of Cellular and Gene Therapy Products: Strategies, Models, and Regulatory Frameworks systematically explores the nonclinical evaluation of Cell and Gene Therapies (CGT) products, emphasizing risk mitigation and innovation. The book provides comprehensive coverage, including 20+ chapters spanning preclinical toxicology, pharmacokinetics, and novel evaluation models. It is the first book to integrate organ-on-chip models into CGT evaluation, reflecting FDA/NMPA modernization initiatives. It includes practical guidance on addressing CRISPR off-target effects, immunogenicity, and long-term carcinogenicity risks. Includes definitions, regulatory policies (US, EU, China), and quality control requirements Provides in-depth coverage of humanized animal models, organ-on-chip systems, and 3D bioprinted tissues for toxicity screening Covers evaluation strategies for mRNA drugs, exosome-based therapies, and red blood cell-mediated drug delivery Includes case studies: FDA-approved CRISPR therapies, CAR-T safety assessments, and lessons from failed trials

Product Specifications

Format
paperback
Domain
Amazon UK
Release Date
05 October 2026
Listed Since
26 February 2026

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