Academic Press Pharmacogenomics: From Research to Clinical Implementation (Translational and Applied Genomics)

Pharmacogenomics: From Research to Clinical Implementation explores the integration of pharmacogenomics into personalized medicine, offering up-to-date knowledge on how genetic variation affects drug response in diverse therapeutic areas such as cardiology, oncology, psychiatry, and more. Beginning with foundational principles, including pharmacodynamics and pharmacokinetics, the book then progresses to advanced topics, including the pharmacogenomics of infectious diseases and organ transplantation, providing readers with both historical context and current advances. Each chapter methodically discusses the application of pharmacogenomics in clinical settings, supported by methods, translational tools, and case studies, ensuring that students, healthcare professionals, and researchers gain practical insights. This book also addresses public health perspectives, including ethical, legal, and economic aspects, making it an indispensable resource for anyone looking to deepen their understanding of pharmacogenomics and its essential role in advancing personalized medicine. Designed to cater for a broad audience, including students, biomedical scientists, and clinicians, Pharmacogenomics not only serves as an educational tool but also as a bridge to clinical practice, emphasizing how pharmacogenetic knowledge can lead to more effective and safer drug therapies. Presents a foundational understanding of pharmacogenomics, covering essential concepts such as pharmacodynamics and pharmacokinetics Explores advanced topics, including the pharmacogenomics of infectious diseases and organ transplantation, integrating historical context with the latest research Details practical applications in clinical settings through comprehensive discussions, translational tools, and relevant case studies Addresses public health perspectives by examining ethical, legal, and economic issues related to pharmacogenomics Bridges the gap between theoretical knowledge and clinical practice, highlighting the role of pharmacogenomics in enhancing drug efficacy and safety