Elsevier Electrocardiography of Laboratory Animals

Electrocardiography of Laboratory Animals, Third Edition, provides the latest information on critical topics such as safety electrocardiography, toxicology, safety pharmacology, and telemetry, ensuring that readers are well-equipped with the knowledge required for accurate ECG interpretation in preclinical studies. The book begins with the fundamental principles of electrocardiography and its applications in drug safety evaluation but then covers electrocardiography in a wide range of laboratory animals, including rodents, guinea pigs, rabbits, cats, dogs, and various non-human primates such as marmosets, cynomolgus monkeys, rhesus monkeys, baboons, and chimpanzees. Additionally, it reviews the ECG characteristics of minipigs, nanopigs, and micropigs. The text also includes chapters on telemetry and echocardiography in preclinical safety studies, as well as discussions on important parameters like PR (PQ), QRS, and QT intervals. The book concludes with chapters on cardiac assays, biomarkers, stem cells, and cardiovascular medical devices, providing a holistic view of cardiovascular research. It is an essential resource for biological and medical researchers, veterinarians, zoologists, and students. Provides standardized methods for performing and analyzing ECGs in all laboratory animal species Covers essential topics like safety pharmacology, toxicology, telemetry, and echocardiography in preclinical studies Includes detailed normal and abnormal ECG variations for rodents, guinea pigs, rabbits, cats, dogs, and non-human primate and pig species Features chapters on cardiac assays, biomarkers, stem cells, and cardiovascular medical devices Offers practical self-assessment ECG rhythm strips to test and enhance diagnostic skills