CRC Press Handbook of Biotransformations of Aromatic Compounds

Understanding the biotransformations of aromatic compounds and how they metabolize in animals, plants, and microbes, is central to the applications in a wide range of industries, such as the design and testing of natural and synthetic pharmaceuticals, oil refining, the development of agrochemicals, bioremediation, and for use in functional genomics and xenobiotics. Presenting the most complete resource of its kind, the Handbook of Biotransformations of Aromatic Compounds examines 20,000 aromatic compounds researched since 1972, and assembled from all the major, relevant journals. The author focuses his coverage on the biotransformation in animals, plants, and microbes while remaining within the scope of aromatic compounds that contain, or are fused with, at least one aromatic C6 ring. Part One lists each compound alphabetically along with the forward and reverse mechanisms of its metabolism in specific organisms. Part Two characterizes the different types of organic reactions that have been identified - including formation and degradation, oxidations and reductions, substitution, and transfer reactions - and the enzymes associated with those reactions. The author cites selected references for enzymes that are well documented while filling in the details for those with little research literature. This book also contains a searchable CD-ROM of the author's previous work covering aromatic compounds researched from 1900 through 1972. Presenting the most complete resource of its kind, this well-established author draws on his firsthand knowledge to organize a large body of information into a user-friendly and indispensable handbook for professionals, policymakers, and researchers alike. Review "The book is indispensable for my work, and for researchers involved in a variety of fields in academia and industry…The author is a world authority on the subject…I HIGHLY recommend this book…" - Dr. Iqbal Gill, Head of Biotransformations/Biocatalysis Department, Roche Vitamins Inc. "…a well-structured book covering the literature of the last thirty years….easy to use and contains plenty of interesting material…contains an immense amount of information on themetabolism of aromatic compounds." ChemBioChem 2005, volume 6 "This book is an excellent and exhaustive source…a labour of love which should prove to be an essential reference source for those involved in the biotransformation of aromatics as it provides detailed coverage of developments within this field over the past 100 years." biochemist.org, July 8, 2005