£48.42

Springer Reelin Glycoprotein: Structure, Biology and Roles in Health and Disease

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Last 58 days • 58 data points (No recent data available)

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£71.06 £34.74 £42.66 £50.59 £58.51 £66.44 £74.36 05 April 2026 19 April 2026 03 May 2026 17 May 2026 01 June 2026

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4 days 34 days 14 days · current 6 days 0 9 17 26 34 £38 £40 £48 £71 Days at Price

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Most common price: £40 (34 days, 58.6%)

Price range: £38 - £71

Price levels: 4 different prices over 58 days

Description

Reelin glycoprotein is a serine protease with important roles in embryogenesis and during adult life. Reelin mutations or deficiency of the protein product could cause abnormal cortical development and reelin signaling impairment in brain. Reelin abnormalities in several neurospychiatric disorders, such as autism, schizophrenia, mood disorders and lissencephaly, may provide mechanistic explanations for etiologies of these disorders. There is also emerging data indicating the feasibility of using various medications (valproic acid, olanzapine) to increase mRNA/protein levels for reelin and/or gene therapy to prevent or treat reelin deficiencies observed in the above-mentioned disorders. This comprehensive and integrative book examines the role that reelin plays in the etiology of various neuropsychiatric disorders, including schizophrenia and autism.

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