Therapeutic Hypothermia: 4 (Molecular & Cellular Biology of Critical Care Medicine, 4) - Image 1

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Springer Therapeutic Hypothermia: 4 (Molecular & Cellular Biology of Critical Care Medicine, 4)

Name: Therapeutic Hypothermia: 4 (Molecular & Cellular Biology of Critical Care Medicine, 4)
Brand: Springer
Price: 150.9 GBP
Availability: InStock

9780387254029

Diseases & Disorders

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Samuel A. Tisherman, MD', Fritz Sterz, MD~ '~niversit~ of Pittsburgh, Pittsburgh, PA, USA 2~edical University of Vienna, Vienna, Austria The use of hypothermia for a variety of therapeutic purposes has a long and erratic history. Hippocrates recommended the use of topical cooling to stop bleeding. Fay used cooling of the extremities for patients with tumors in the 1930s. It wasn't until the 1950s, when the effects of hypothermia on systemic oxygen metabolism became better defined, that systemic hypothermia became a commonly used modality, particularly for cardiac surgery. Hypothermia was used for protection (treatment before the insult) and preservation (treatment during the insult) of the heart and entire organism during planned operative ischemia. Shortly thereafter, attempts were made to use hypothermia for resuscitation (treatment after the insult) from cardiac arrest and for management of head trauma. At that time, it was felt that moderate hypothermia (28-32OC) was needed. This was difficult to achieve and manage. Multiple complications were noted. Consequently, therapeutic, resuscitative hypothermia lay dormant for many years while mild (32-35°C) to moderate hypothermia became common for many cardiothoracic and neurosurgical procedures. In the early 1990s, it was found that mild hypothermia, even after cardiac arrest, had benefit for the brain. Similar results were found with head trauma. This lead to a burst of enthusiasm for research into resuscitative hypothermia for a variety of insults, most of which have tissue ischemia as a major component.

Product Specifications

Brand: Springer
Model: 9780387254029
Format: hardcover
ASIN: 0387254021
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Diseases & Disorders
Domain: Amazon UK
Release Date: 09 June 2005
Listed Since: 10 December 2006

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Springer Therapeutic Hypothermia: 4 (Molecular & Cellular Biology of Critical Care Medicine, 4)

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