Mammalian Heme Peroxidases: Diverse Roles in Health and Disease: 47 (Oxidative Stress and Disease) - Image 1

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CRC Press Mammalian Heme Peroxidases: Diverse Roles in Health and Disease: 47 (Oxidative Stress and Disease)

Name: Mammalian Heme Peroxidases: Diverse Roles in Health and Disease: 47 (Oxidative Stress and Disease)
Brand: CRC Press
Price: 136.0 GBP
Availability: InStock

Immunology

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Mammalian heme peroxidase enzymes play a critical role in innate immune responses and disease prevention. The formation of potent chemical oxidants is essential to this protective physiologic activity in immunity. Although highly beneficial in the context of immune defense, it is now well established that peroxidases and their overproduction of oxidants contribute to the initiation and persistence of many chronic inflammatory conditions in the cardiovascular, neurologic, respiratory, renal, and gastrointestinal systems. Peroxidasins, a protein family related to heme peroxidases, play a novel role in tissue biogenesis and matrix assembly, which are also attracting attention in different pathological contexts. Given the diverse roles of mammalian heme peroxidases and the breadth and incidence of pathologies associated with these enzymes, there has been significant interest in modulating peroxidase activity as a therapeutic strategy. This book highlights recent developments in our understanding of the chemistry, biochemistry and biological roles of mammalian peroxidases and their associated oxidants, their involvement in both innate immunity and chronic inflammatory disease in a variety of end organs, and potential therapeutic approaches to modulate and prevent damaging reactions. Key Features Structure and biosynthesis of mammalian peroxidases Reactivity of hypohalous acids with biological substrates Peroxidases in innate immunity Peroxidases in human pathology Modulation of peroxidase-induced biological damage

Product Specifications

Brand: CRC Press
Format: hardcover
ASIN: 0367820366
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Diseases & Disorders > Immunology
Domain: Amazon UK
Release Date: 08 October 2021
Listed Since: 28 March 2021

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CRC Press Mammalian Heme Peroxidases: Diverse Roles in Health and Disease: 47 (Oxidative Stress and Disease)

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CRC Press Mammalian Heme Peroxidases: Diverse Roles in Health and Disease: 47 (Oxidative Stress and Disease)

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