Academic Press Visceral Leishmaniasis: Therapeutics and Vaccines (Developments in Immunology)

Product Description Visceral Leishmaniasis: Therapeutics and Vaccines describes current therapeutics, natural anti-leishmanial molecules, anti-leishmanial screening, and explores vaccine candidates and amastigote-based vaccination strategies for Leishmania. The book provides a precise view on VL, Leishmania parasite culture, host immunity and immunomodulation, natural compounds effective against VL, animal models for VL, and methodologies available for anti-leishmanial drug screening procedures against VL, as well as vaccine and vaccination-related information on Leishmaniasis.  Readers will find concrete information on past and current hurdles facing vaccine development for Leishmania, along with scientific opportunities and the potential impact of vaccines, including problems encountered. The book is designed to increase the understanding of vaccines, particularly in VL, for students and researchers. Although vaccines are now available for many diseases, there are still challenges ahead for a vaccine for VL. The ideal vaccine must be safe and able to induce an immune response that is strong and effective. In a nutshell, a combination of chemotherapy (drugs) and immunoprophylaxis (vaccine) would be ideal to win the battle against VL. Review Provides the latest on Visceral Leishmaniasis, including drug screening and the state-of-the-art on novel approaches and methodologies for vaccines From the Back Cover Visceral Leishmaniasis: Therapeutics and Vaccines covers the therapeutic and vaccine aspects of a fatal disease Visceral Leishmaniasis (VL) in a single volume. Visceral Leishmaniasis: Therapeutics and Vaccines describes substantially current therapeutics, natural anti-leishmanial molecules, anti-leishmanial screening, and explores vaccine candidates and amastigote-based vaccination strategy for Leishmania in 14chapters. It provides a precise view on VL, Leishmania parasite culture, host immunity and immunomodulation, natural compounds effective against VL, animal models for VL, and methodologies available for anti-leishmanial drug screening procedures against VL, as well as vaccine and vaccination-related information on Leishmaniasis. Visceral Leishmaniasis: Therapeutics and Vaccines also provides concrete information on past and current hurdles facing vaccine development for Leishmania and reveals the scientific opportunities and potential impact of vaccines, including problems encountered. Future challenges for vaccines against VL and immunization are discussed. Visceral Leishmaniasis: Therapeutics and Vaccines is designed to increase the understanding of vaccines, particularly in VL, for students and researchers. Although vaccines are now available for many diseases, there are still challenges ahead for a vaccine for VL. The ideal vaccine must be safe and able to induce an immune response that is strong and effective. In a nutshell, a combination of chemotherapy (drugs) and immunoprophylaxis (vaccine) could be ideal to win the battle against VL. Scientists from both academic fields and industry, who are involved in infection biology, biomedical research, and drug development, will find a valuable and fundamental guide in Visceral Leishmaniasis: Therapeutics and Vaccines that conveys the information necessary to understand and to improve the success in combating this disease worldwide. About the Author Dr. Awanish Kumar is currently Associate Professor at the National Institute of Technology. He has a PhD in Biotechnology from the McGill University,. Canada. He is the editor of 8 books, 18 book chapters and 124 journal articles. He has 12 years of research experience and 8 years of teaching experience.