Antisense Technology in the Central Nervous System - Image 1

£59.95

Oxford University Press Antisense Technology in the Central Nervous System

Name: Antisense Technology in the Central Nervous System
Brand: Oxford University Press
Price: 59.95 GBP
Availability: InStock

Neurology & Clinical Neurophysiology

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Description

Antisense technology has been used for several years to "knock down" the expression of specific genes in living tissues to study the functions of their protein products. Specifically designed antisense oligonucleotides (ODNs) are short lengths of man-made genetic material designed to interfere with the production of the protein encoded by the gene. This can shed light on the function of the protein; alternatively, if a disease process results from an excess of a certain protein, the method can in theory correct the problem. Although faster than transgenic techniques, antisense has been seen as something of a "black art". There are many technical problems to understand and overcome. This is the first book to provide a critical review of the uses of this technology in the central nervous system. It includes: Background to the technology Problems of design and synthesis of antisense molecules Administration in the brain Protection of ODNs from metabolic destruction

Product Specifications

Brand: Oxford University Press
Format: paperback
ASIN: 0198505388
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Neurology & Clinical Neurophysiology
Domain: Amazon UK
Release Date: 14 October 1999
Listed Since: 19 October 2006

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Oxford University Press Antisense Technology in the Central Nervous System

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