£147.37

Elsevier Benzodiazepine-Based Drug Discovery (Heterocyclic Drug Discovery)

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£154.73 £141.23 £144.18 £147.12 £150.07 £153.01 £155.96 09 June 2024 09 November 2024 11 April 2025 11 September 2025 11 February 2026

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107 days 254 days 165 days 63 days · current 11 days 9 days 4 days 0 64 127 191 254 £143 £145 £146 £147 £148 £149 £155 Days at Price

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Most common price: £145 (254 days, 41.4%)

Price range: £143 - £155

Price levels: 7 different prices over 613 days

Description

Benzodiazepine-Based Drug Discovery covers benzodiazepines and benzothiazepines, which constitute two pivotal classes of heterocyclic compounds widely used as core structures of medicinal drugs for the treatment of depression, epilepsy, seizures and muscle spasms. 1,4-Benzodiazepine, 1,5-benzodiazepine, and 1,5-benzothiazepine are the most studied groups of benzodiazepines and benzothiazepines because of their outstanding potential biological activities. This book offers a broad range of recent developments and detailed coverage of the synthesis and biological activities of the drugs based on benzodiazepine and benzothiazepine matrixes, and is an ideal reference guide to researchers working in organic and medicinal chemistry. The importance of these privileged pharmacophores is not limited to the treatment of psychotic disorders because minor changes in the structures can generate various biological activities. They represent a wide range of therapeutic functions such as anticonvulsant, antianxiety, anti-depressant, antiviral, anti-HIV, anti-inflammatory, anticoagulant, anti-obesity, endothelin antagonist, cholecystokinin antagonist, and vasopressin receptor antagonist activities. Presents detailed coverage of chemical structures and practical synthetic methods of benzodiazepines and benzothiazepines in drug discovery Compiles detailed in vivo and in vitro biological activity data of 1,4-benzodiazepine- and 1,5-benzodiazepine-based drugs that will help researchers design and develop innovative drugs Discusses promising avenues and potential challenges in the development of new benzodiazepines and benzothiazepines in medicinal drug synthesis

Product Specifications

Format
Paperback
Domain
Amazon UK
Release Date
22 August 2022
Listed Since
07 October 2020

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