Elsevier Direct Nose-to-Brain Drug Delivery: Mechanism, Technological Advances, Applications, and Regulatory Updates

Direct Nose to Brain Drug Delivery: Mechanism, Technological Advances, Applications and Regulatory Updates provides the reader with precise knowledge about the strategies and approaches for enhanced nose to brain drug delivery. It highlights the development of novel nanocarrier-based drug delivery systems for targeted drug delivery to the brain microenvironments with a focus on the technological advances in the development of the novel drug delivery devices for intranasal administration, including special emphasis on brain targeting through nose. This book explores the various quantification parameters to assess the brain targeting efficiency following intranasal administration, includes an overview on the toxicity aspects of the various materials used to develop the direct nose to brain drug delivery vehicles and of the regulatory aspects including patents and current clinical status of the potential neurotherapeutics for the effective management of neuro-ailments. Technological advances in new drug delivery systems with diverse applications in pharmaceutical, biomedical, biomaterials, and biotechnological fields are also explained. Direct Nose to Brain Drug Delivery: Mechanism, Technological Advances, Applications and Regulatory Updates is a crucial source that will assist the veteran scientists, industrial technologists, and clinical research professionals to develop new drug delivery systems, and novel drug administration devices for the treatment of neuro-ailments. Explains the targeting approaches for enhanced brain targeting following intranasal drug administration Explores the various nanocarriers developed to date for neurotherapeutic delivery via nose to brain Discusses pharmaceutical and biomedical applications after nose to brain delivery of therapeutic pharmaceuticals and biologicals