Academic Press Hyperpolarized Carbon-13 Magnetic Resonance Imaging and Spectroscopy: Volume 3 (Advances in Magnetic Resonance Technology and Applications, Volume 3)

MRI with hyperpolarized carbon-13 agents is a powerful emerging imaging modality that can measure real-time metabolism in cells, animals, and humans. It uses endogenous, non-toxic contrast agents that a hyperpolarized, resulting in up to 100,000-fold increases in sensitivity. This technique uses no ionizing radiation, and is being applied in a range of human trials. It’s primary use is for metabolic imaging, but it can also measure perfusion, pH, and necrosis. Hyperpolarized Carbon-13 Magnetic Resonance Imaging and Spectroscopyis designed to be a one stop shop for understanding hyperpolarized 13C MRI. This book explains the principles of this imaging modality, the requirements for performing studies, shows how to interpret the results, and gives an overview of current biomedical applications. It is suitable for engineers, scientists and clinicians in radiology and biomedical imaging who want to understand this technology. Review Presents the principles of MRI with hyperpolarized carbon-13 agents, its requirements for studies, how to interpret results, and more From the Back Cover MRI with hyperpolarized carbon-13 agents is a powerful emerging human imaging modality that can measure real-time metabolism; it uses endogenous, non-toxic contrast agents with no ionizing radiation, and is being applied to early stage human trials. It’s primary use is for metabolic imaging, but it can also measure perfusion, pH, and necrosis. This book explains the principles of this imaging modality (explaining how it works), the requirements for performing studies, shows how to interpret the results, and gives an overview of current biomedical applications. Hyperpolarized Carbon-13 Magnetic Resonance Imaging and Spectroscopy is designed to be a one stop shop for understanding HP 13C MRI, providing an understanding of the principles as well as the rapidly evolving state-of-the-art of this technology. It is very suitable for engineers, scientists and clinicians in radiology and biomedical imaging who want to understand this technology. With this book the reader can: Design a hyperpolarized carbon-13 MR experiment Perform a hyperpolarized carbon-13 MR experiment Analyze and interpret hyperpolarized carbon-13 MR data About the Author Peder Larson, PhD, is an Associate Professor in Residence and a Principal Investigator in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. Dr. Larson's research program is primarily centered around developing new MRI scanning and reconstruction technology for improved clinical outcomes Dr. Peder Larson got his PhD under Dwight Nishimura from the Department of Electrical Engineering at Stanford University on "MRI of Semi-solid Tissues" in 2007. His research interests are in RF pulse design, pulse sequence development, novel imaging strategies, and optimized reconstruction methods for MRI, with an emphasis on applications in Hyperpolarized carbon-13 agents and semi-solid tissue imaging with ultrashort echo time (UTE) methods.