Woodhead Publishing Long-Acting Drug Delivery Systems: Pharmaceutical, Clinical, and Regulatory Aspects (Woodhead Publishing Series in Biomaterials)

Long-Acting Drug Delivery Systems: Pharmaceutical, Clinical, and Regulatory Aspects offers a comprehensive overview of the technical, clinical, regulatory and industrial perspectives on these drug delivery systems. The book follows a sequential order, beginning with the current technical state-of-the-field and moving on to more clinical, industrial and regulatory topics. Opening chapters describe the current needs and potential applications of implantable and long-acting therapeutic approaches. The book goes on to describe established and novel long-acting systems, with a focus on the materials used to prepare these systems and their biocompatibility. Importantly, applied topics such as scale-up manufacturing, products under clinical trials and regulatory aspects are covered, offering the reader a holistic view of this rapidly growing field. Review A comprehensive overview of long-acting and implantable drug delivery systems, including basic science, clinical applications and regulatory perspectives From the Back Cover Long-Acting Drug Delivery Systems: Pharmaceutical, Clinical, and Regulatory Aspects offers a comprehensive overview of the technical, clinical, regulatory and industrial perspectives on these drug delivery systems. Implantable and long-acting drug delivery systems are systems that offer the possibility of unattended and localized long lasting therapies. Accordingly, they offer multiple advantages over conventional drug delivery systems, such as improving patient compliance while reducing the required drug dosage, which is especially important for the treatment of chronic conditions. Long-Acting Drug Delivery Systems: Pharmaceutical, Clinical, and Regulatory Aspects follows a sequential order, beginning with the current technical state of the field and moving on to more clinical, industrial and regulatory topics. Opening chapters describe the current needs and potential applications of implantable and long-acting therapeutic approaches. The book goes on to describe established and novel long-acting systems, with a focus on the materials used to prepare these systems and their biocompatibility. Importantly, applied topics such as scale-up manufacturing, products under clinical trials and regulatory aspects are covered, offering the reader a holistic view of this rapidly growing field. About the Author Dr Eneko Larrañeta is a Lecturer in Pharmaceutical Sciences at the School of Pharmacy Queen’s University Belfast. He worked in different multidisciplinary first-class laboratories developing drug delivery systems. His research area falls within the interface of pharmaceutics, chemistry, engineering and biomedical sciences. During his independent career, he developed research projects for industrial partners (L’Oreal) and research councils (Wellcome Trust, Royal Society, PATH among others). To date, he has published more than 40 peer-reviewed papers in leading international journals, as well as 4 book chapters, 1 invited presentation and 11 conference abstracts, describing a range of advanced drug delivery systems, including nanoparticles and microneedles. Dr Thakur obtained his PhD in Drug Delivery from School of Pharmacy, Queens University Belfast (2009), M.Sc in Pharmaceutical Sciences from University Science Malaysia (2006) and B.Pharm from Jawaharlal Nehru Technological University, India (2002). His current research involves the fabrication and design of novel long-acting injectable and implantable drug delivery systems for treating back of the eye disorders. Dr Thakur's ocular drug delivery research has led to the formation of Re-Vana?Therapeutics Ltd. He is currently acting as the CSO for Re-Vana. He is Chair for Ocular Delivery (OcD) Focus Group?supported by the mission of Controlled Release Society (CRS). He has authored over 150 scientific publications, including 52 peer-reviewed research papers, 10 book chapters and 4 textbooks. He has been an