Academic Press Trichinella and Trichinellosis

Trichinella and Trichinellosis provides an up-to-date account of the nematode Trichinella spp., including infections and diseases caused by this parasite in both animals and humans. This book will fill the long gap in time during which an exhaustive monograph on this subject has been missing in the international literature. The chapters have been written by the most prolific researchers in the world on the different aspects of Trichinella and trichinellosis. This book serves as an original resource for research on Trichinella and trichinellosis, exploring cutting-edge advances on such parasites and the infections they cause. This book will be a valuable resource for students, biologists, epidemiologists, veterinarians, physicians, and scientists involved in the study of the parasites of the Trichinella genus and their related diseases. It will be particularly helpful for those who are beginning their research in this fascinating field. Review Serves as an original resource for the research on Trichinellosis exploring cutting-edge advances on this infectious disease From the Back Cover Immunology of Trichinellosis describes different aspects of the host immune response to Trichinella. The role of antibodies, T cells, mast cells, eosinophils and neutrophils in immune reaction to this nematode is considered, in the light of the recent data derived from experimental models, both in in vivo and in vitro. The knowledge of immune response mechanisms against Trichinella is fundamental to understand how the nematode can escape such mechanisms. The principal evasion mechanisms of host immune response occurring in trichinellosis are described, particular attention is focused on immunomodulation and the possibilities to verify the effects on immuno-mediated diseases. In conclusion, some considerations on the actual ability to escape the host immune response are discussed, taking into account the recent data that shows that the nematode might rather drive immune system of the host towards a less dangerous response. About the Author Fabrizio Bruschi is a professor of parasitology and parasitic diseases at the School of Medicine, Università di Pisa, Italy. Prof. Bruschi has been a member of the International Commission on trichinellosis since 1988. Additionally, he is currently President of the Italian Society of Parasitology (SoIPa). Furthermore, he is a corresponding member of the National School of Tropical Medicine (NSTM) at the Baylor College of Medicine, Houston, United States.