Academic Press Enzyme Active Sites and their Reaction Mechanisms

Enzyme Active Sites and their Reaction Mechanisms provides a one-stop reference on how enzymes "work." Here, Dr. Harry Morrison, PhD and Professor Emeritus at Purdue University, provides a detailed overview of the origin and function of forty enzymes, the chemical details of their active sites, their mechanisms of action, and associated cofactors. The enzymes featured highlight a step forward, along with possible areas of application, thus supporting new research in academic and industrial labs. Each chapter is written in a clear format, including a brief summary of enzyme function and structure, a detailed description of their mechanisms of action and associated co-factors. Review Offers a detailed overview on the origin and function of enzymes, the chemical details of their active sites, mechanisms of action, and related co-factors From the Back Cover With ever advancing experimental and computational methodologies, we now have a wealth of detail on how enzymes function at the biochemical and molecular level. Enzyme Active Sites and their Reaction Mechanisms provides a one-stop reference for those seeking to understand how enzymes "work." Here, Dr. Harry Morrison, PhD and Professor Emeritus at Purdue University provides a detailed overview of the origin and function of forty enzymes, the chemical details of their active sites, and their mechanisms of action, as well as that of any associated cofactors. The enzymes featured each highlight a recent step forward in the field and possible areas of application, supporting new research in academic and industrial labs. Each chapter is written in a clear, digestible format for easy use, including a brief summary of enzyme function and structure, followed by a detailed description of their mechanisms of action and associated co-factors. Additionally, an introductory chapter describes the relationship between new and evolving experimental approaches (e.g. X-ray crystallography), and recent advances in our knowledge of enzyme active sites and their reaction mechanisms. About the Author Harry Morrison, PhD is Emeritus Professor at Purdue University, West Lafayette, IN, USA. He joined the Purdue School of Science in 1963, and has since supervised nearly fifty Ph.D. students, and also served as Dean of the College of Science from 1992-2002. Dr. Morrison was instrumental in increasing the numbers and impact of women faculty in the College of Science. After earning a B.A. from Brandeis University in 1957 and a Ph.D. from Harvard in 1961, Dr. Morrison was a Postdoctoral Researcher at the Swiss Federal Institute in Zurich, Switzerland for two years, and following this was a Research Associate at the University of Wisconsin from 1962-1963. Dr. Morrison has published over 170 papers in peer reviewed journals and has edited two books on bioorganic chemistry.