Academic Press Muscle Biology: The Life History of a Muscle

Muscle Biology: The Life History of a Muscle looks at the story of a muscle from its embryonic beginnings, through its growth and ability to adapt to changing functional circumstances during adult life, to its eventual decline in both structure and function as old age progresses. Injury occurs to muscle during normal activity, after trauma, and during the source of certain diseases. Chapters on both muscle regeneration and muscle diseases emphasize the possibilities and limitsations of the healing capacity of muscle fibers. Muscle Biology begins with a brief review about the structure and function of a normal mature muscle and then proceeds to follow the developmental history of a muscle from the embryo to old age in a manner that gives the reader a perspective about not only developmental controls but also how at any stage of development a muscle is able to adapt to its functional environment. The book discusses both normal and abnormal changes in the muscle, the mechanisms behind those changes and how to mitigate deleterious changes from disease, 'normal' aging, and disuse/lack of physical activity. This is a must-have reference for students, researchers and practitioners in need of a comprehensive overview of muscle biology. Review Provides an overview of skeletal muscle biology over the course of one’s lifespan, from the embryonic origins of muscle to muscle in extreme old aging, while also covering skeletal muscle development, pathology, changes in training and regeneration From the Back Cover <p><i>Muscle Biology: The Life History of a Muscle</i> tells the story of a muscle, from its embryonic origins to its condition at the end of life. This book uses the leg muscle, a tightly knitted group, the quadriceps femoris, which consists of four individual muscles (rectus femoris, vastus lateralis, vastus medialis and vastus intermedius) to provide an in-depth look at skeletal muscle biology. It covers the development of the muscle, muscle pathology, changes in the muscle from training and muscle regeneration.</p> <p><i>Muscle Biology: The Life History of a Muscle</i> conveys basic specific information about the various aspects of a muscle’s existence and educates readers to the fact that muscle can be viewed as a continuum of developmental events so that readers get a broad review of the essential ways that muscles adapt to their environment over the course of a lifetime. The book discusses both normal and abnormal changes in the muscle, the mechanisms behind those changes and how to mitigate deleterious changes from disease, ‘normal aging, and disuse/lack of physical activity. This is a must-have reference for students, researchers and practitioners in need of a comprehensive overview of muscle biology.</p> About the Author Dr. Carlson serves as Professor Emeritus of Anatomy in the Department of Cell and Developmental Biology in the University of Michigan Medical School in Ann Arbor. Dr. Carlson is the author of more than fifteen book publications including several books published by Elsevier (Human Embryology and Developmental Biology 1-5/e, Principles of Regenerative Biology, repurposed embryology and physiology texts for Elsevier’s digital Reference Module in Biomedical Sciences in 2014). Dr. Carlson has served as president of the American Association of Anatomists, and president of the Association of Anatomy, Cell Biology, and Neurobiology Chairpersons. Additional honors include the AAAS Newcomb-Cleveland Prize, membership in the Russian Academy of Natural Sciences, and the Henry Gray Award of the American Association of Anatomists. An accomplished teacher, Dr. Carlson has received both the Elizabeth Crosby Teaching Award and the Kaiser-Permanente Teaching Award from the University of Michigan Medical School.