Academic Press Multiscale Biomechanical Modeling of the Brain

Multiscale Biomechanical Modeling of the Brain discusses the constitutive modeling of the brain at various length scales (nanoscale, microscale, mesoscale, macroscale and structural scale). In each scale, the book describes the state-of-the- experimental and computational tools used to quantify critical deformational information at each length scale. Then, at the structural scale, several user-based constitutive material models are presented, along with real-world boundary value problems. Lastly, design and optimization concepts are presented for use in occupant-centric design frameworks. This book is useful for both academia and industry applications that cover basic science aspects or applied research in head and brain protection. The multiscale approach to this topic is unique, and not found in other books. It includes meticulously selected materials that aim to connect the mechanistic analysis of the brain tissue at size scales ranging from subcellular to organ levels. Review Presents constitutive models of the brain at various length scales (nanoscale, microscale, mesoscale, macroscale and structural scale) From the Back Cover <p>Multiscale biomechanical modeling of the brain presents a robust description of the constitutive modeling of the brain at the various length scales (nanoscale, microscale, mesoscale, macroscale and structural scale). In each scale, the book goes through to the state-of-the- experimental and computational tools used to quantify critical deformational information at that length scale. Then, at the structural scale, several user-based constitutive material models are presented along with its real-world boundary value problems. Lastly, design and optimization concepts are presented for use in occupant-centric design framework.</p> <p>This book is useful for both academia and industry where there is focus on the basic science aspects or the applied research of head and brain protection. The multiscale approach to this topic is unique, and cannot be found in other books. This book includes meticulously selected materials that aim at interconnecting the mechanistic analysis of the brain tissue at size scales ranging from subcellular to organ levels, and is an excellent reference for students, researchers, and clinicians in the field of brain mechanics and trauma.</p> About the Author CAVS Chair Professor, Department of Mechanical Engineering, Mississippi State University Dr. Horstemeyer has published over 350 journal articles, conference papers, books, and technical reports. He has won many awards including the R&D 100 Award, AFS Best Paper Award, Sandia Award for Excellence, the SAE Teetor Award and was a consultant for the Columbia Accident Investigation Board. He is a fellow of the American Society of Mechanical Engineers, the American Society of Metals, the American Association for the Advancement of Science, and the Society of Automotive Engineers. Before coming to MSU, he worked at Sandia National Laboratories for 15 years where he worked on a myriad of projects mostly focusing on weapons programs but transferred the research and technologies developed at Sandia to the automotive industry. Dr. Raj K. Prabhu is the Deputy Project Scientist, NASA Human Research Program’s (HRP’s) Cross-Cutting Computational Modeling Project (CCMP) at Universities Space Research Association. In his current position, Dr. Prabhu supports CCMP’s computational modeling efforts to investigate human physiological responses to space stressors and provide modeling and simulation-based support to mitigate HRP-related risks. Before the CCMP role, Dr. Raj Prabhu jointly served as an Associate Professor of Biomedical Engineering and Associate Director at the Center for Advanced Vehicular Systems, Mississippi State University (MSU), Starkville, MS. Dr. Prabhu obtained his doctoral and master’s degrees in mechanical engineering and computational engineering respecti