Academic Press Introduction to Addiction: Addiction, Animal Models, and Theories: Volume 1 (Neurobiology of Addiction Series, Volume 1)

Product Description Introduction to Addiction, Volume One in the series, introduces the reader to the study of neurobiology of addiction by clearly defining addiction and its neuroadaptational views. This volume includes thorough descriptions of the various animal models applicable to the study of addiction, including Animal Models of the Binge-Intoxication Stage of the Addiction Cycle and Animal Models of Vulnerability to Addiction. The book's authors also include a section on numerous neurobiological theories that aid in the understanding of addiction, including dopamine, prefrontal cortex and relapse. Provides neurobiological theories on how addiction works Explains addiction cycle stages of binge, withdrawal and anticipation Reviews the role of dopamine and the frontal cortex in addiction Discusses the neurocircuitry of reward and stress Includes animal models and neuroadaptational views on addiction Review "This book, Introduction to Addiction by Koob, Arends, McCracken and Le Moal, has thoroughly documented the tremendous progress in the field of neurobiology of addiction from molecular to brain circuitry to behavioral pharmacology. The conceptual frameworks of the various cycles of addiction and recruitment of brain circuits and neurobiological substrates to drive addiction are very well presented in this book. I found all three chapters, “What is Addiction?, “Animal Models of Addiction, and “Neurobiological Theories of Addiction, exceptionally well presented and worth the time of any person interested in this field. This book provides helpful and succinct comparisons of addiction in humans and face validity of animal models to cover various aspects of behaviors. This book provides extraordinary coverage of the research underlying the neurobiological basis of addiction. It was a great pleasure to read and I highly endorse this book." --Subhash C. Pandey, PhD, Professor and Director, Alcohol Research Center, Dept. of Psychiatry, University of Illinois at Chicago & Senior Research Career Scientist "According to a 2018 World Health Organization report*, harmful use of alcohol results in 3.3 million deaths annually in the 38% of the drinking population; another 31 million people are affected with drug use disorders. These statistics indicate an urgency to recognize and treat this worldwide burden on health and well-being, which requires a fundamental biological understanding. To maintain stride with current concepts of addiction, any level of student, scientist, or clinician who is seriously interested in addiction and its neurobiological basis will find volume one an essential addition to their library. Indeed, this volume is far more than a simple expansion of the 2006 Neurobiology of Addiction by Koob and Le Moal in presenting descriptions, explanations, and summaries of theories and models of addiction with rigorous, research-based foundations. Each section is replete with relevant peer-reviewed citations, providing the reader a ready start to dig deeply into areas of particular interest. Remarkably, the authors present a clearly written volume, despite the density of its information. The organization of the book enhances its readability by presenting individual scholarly reviews of the many theories of addiction, copious references (544 references in this volume alone), and the welcome ending paragraphs printed in italics that present fair summaries of each theory. Complementing these features is the artwork, which describes brain circuits and associated behaviors that may be disturbed with different phases of addiction according to the reviewed model or theory. The inclusion of cognitive, sensory, motor, and emotional factors as central considerations in a volume on the neurobiology of addiction shows a critical sensitivity to the problem of addiction itself, what makes it important in human behavior, how different drugs of addiction affect selective neurocircuitry and associated behavior, and how each can have