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£137 today · previous high £137 · all-time low £129

Elsevier Neuronal Chloride Transporters in Health and Disease

Amazon

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£137.29 £128.71 £130.58 £132.45 £134.33 £136.20 £138.07 25 July 2026 09 August 2026 24 August 2026 08 September 2026 24 September 2026
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Most common price: £135 (38 days, 61.3%)

Price range: £129 - £137

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Description

In the past several years, there has been an exciting body of new research that links impairments in the expression or function of neuronal chloride transporters to a growing number of diseases spanning from autism to brain aging. This book introduces the core concepts and highlights the recent advances in understanding the physiology and pathophysiology of the KCC and NKCC families of neuronal chloride transporters. Neuronal chloride transporter biology is reviewed, including roles in setting the transmembrane chloride gradient and the chloride transport-independent functions, such as regulating excitatory neurotransmission. Chapters are also dedicated to addressing the structure, post-translational modification, membrane trafficking, and protein interaction partners of neuronal chloride transporters, as well as the genetic and environmental factors that regulate their expression in neurons and the novel therapeutic approaches that target neuronal chloride transporters to treat neurological diseases. This new volume will provide readers with an up-to-date summary of the recent advances in neuronal chloride transporter research, with particular emphasis on some of the key emerging topics in the field.

Product Specifications

Format
paperback
Domain
Amazon UK
Release Date
07 January 2020
Listed Since
11 October 2019

Barcode

No barcode data available

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