Academic Press Advances in Physical Organic Chemistry (Volume 52)

Advances in Physical Organic Chemistry, Volume 52 in the series, is the definitive resource for authoritative reviews of work in physical organic chemistry. It aims to provide a valuable source of information that is ideal not only for physical organic chemists applying their expertise to both novel and traditional problems, but also for non-specialists across diverse areas who identify a physical organic component in their approach to research. Its hallmark is a quantitative, molecular level understanding of phenomena across a diverse range of disciplines. Reviews the application of quantitative and mathematical methods to help readers understand chemical problems Provides the chemical community with authoritative and critical assessments of the many aspects of physical organic chemistry Covers organic, organometallic, bioorganic, enzymes and materials topics Presents the only regularly published resource for reviews in physical organic chemistry Written by authoritative experts who cover a wide range of topics that require a quantitative, molecular-level understanding of phenomena across a diverse range of disciplines Review Continually publishes cutting-edge reviews in the field of physical organic chemistry, containing results and methodologies About the Author Ian Williams has been Professor of Theoretical Organic Chemistry at the University of Bath since 1995. He has many years’ experience in the application of computational methods to the study of problems in physical organic chemistry. Born in Bournemouth, England, he studied at the University of Sheffield and gained his PhD under the supervision of James McKenna. He then spent two years in Richard Schowen’s laboratory at the University of Kansas, five years as a Royal Society Pickering Research Fellow at Cambridge in the sub-group of Theoretical Chemistry, and four years as an EPSRC Advanced Fellow in Bristol. Since his first appointment at Bath in 1989, he has taught physical organic and computational chemistry to all years of the Chemistry programmes and is currently a Director of Studies. His research uses computational modelling and simulation as tools to aid the interpretation of experimental observations, and he has published on a broad range of topics from atmospheric chemistry to enzyme mechanisms. A past Chair of the Royal Society of Chemistry Theoretical Chemistry Group and UK representative on the EuCheMS Division of Computational Chemistry, he now serves on the IUPAC Subcommittee on Structural and Mechanistic Chemistry, which has responsibility for the ICPOC international conferences on physical organic chemistry, and he chaired ICPOC21 in the UK. He is no relation to the other Co-Editor of Advances in Physical Organic Chemistry! Nick Williams has been Professor of Physical Organic Chemistry at the University of Sheffield since 2011. He has many years experience in experimental studies that are focused on understanding mechanism and reactivity in organic chemistry. He studied for his first degree at the University of Cambridge, where he stayed for his PhD under the supervision of Tony Kirby. After a further short post doctoral period and a position as temporary lector in organic chemistry at Trinity College, Cambridge, he spent two years at McGill University in the laboratory of Jik Chin as a Royal Society/NSERC research fellow. He was appointed to a lectureship in Sheffield in 1996, where he has remained since, and has taught physical organic chemistry at all undergraduate levels and is currently Chair of the Curriculum Committee. His research involves the design, synthesis and analysis of organic and inorganic compounds to dissect and quantify contributions to reactivity and catalysis. This has been particularly focused on biologically relevant reactions and artificial models that functionally mimic natural systems, but has embraced topics as diverse as light induced surface patterning and transmembr