Academic Press Computational Epigenetics and Diseases (Volume 9) (Translational Epigenetics, Volume 9)

Computational Epigenetics and Diseases, Ninth Edition provides a comprehensive and cutting-edge knowledge of computational epigenetics in human diseases as written by leading scientists in this evolving field. In particular, the major computational tools, databases and strategies for computational epigenetics analysis, for example DNA methylation, and histone modifications and microRNA are summarized. The book discusses bioinformatics methods for epigenetic analysis as they apply to human conditions, such as aging, atherosclerosis, diabetes mellitus, schizophrenia, bipolar disorder, Alzheimer, Parkinson, liver and autoimmune disorders, and reproductive and respiratory diseases. Additionally, different organ cancers are discussed, including breast, lung and colon. This book is a valuable source for graduate students and researchers on genetics and bioinformatics, and for biomedical field members interested in applying computational epigenetics in their research. Provides a comprehensive and cutting-edge knowledge of computational epigenetics in human diseases Summarizes the major computational tools, databases and strategies for computational epigenetics analysis, such as DNA methylation, histone modifications and microRNA Covers the major milestones and future directions of computational epigenetics in various kinds of human diseases, such as aging, atherosclerosis, diabetes, heart disease, neurological disorders, cancers, blood disorders, liver diseases, reproductive diseases, respiratory diseases, autoimmune diseases, human imprinting disorders and infectious diseases Review An overview of the current state of computational epigenetics and how it contributes to the diagnosis, treatment and management of human diseases About the Author Loo Keat Wei is Doctor of Philosophy on Human Genetics by Universiti Sains Maysia. Dr. Loo is a young scientist in Malaysia, who has showed a great interest and curiosity in the field of computational epigenetics. She has published several articles in this emerging field and has been awarded many prestigious international and national research grants such as Australia Endeavour Award, Ministry of Higher Education Fundamental Research Grant Scheme, Research Publication Schemes, Universiti Tunku Abdul Rahman Research Funds, etc., successfully securing more than USD $200,000 funds in the last three years. She is the member of International Stroke Genetics Consortium, Reviewer and Editorial Board Member in multiple journals.