Academic Press A Comprehensive Physically Based Approach to Modeling in Bioengineering and Life Sciences

A Comprehensive Physically Based Approach to Modeling in Bioengineering and Life Sciences provides a systematic methodology to the formulation of problems in biomedical engineering and the life sciences through the adoption of mathematical models based on physics principles, such as the conservation of mass, electric charge, momentum, and energy. It then teaches how to translate the mathematical formulation into a numerical algorithm that is implementable on a computer. The book employs computational models as synthesized tools for the investigation, quantification, verification and comparison of different conjectures or scenarios of the behavior of a given compartment of the human body under physiological and pathological conditions. Presents theoretical (modeling), biological (experimental), and computational (simulation) perspectives Features examples, exercises, and MATLAB codes for further reader involvement Covers basic and advanced functional and computational techniques throughout the book Review "When this reviewer opted to receive and review this text, it was hoped that it would present as a complementary text to those of Drs. Carson and Cobelli [Modelling Methodology for Physiology and Medicine (2013) and Introduction to Modeling in Physiology and Medicine, 2nd ed. (2019)]. This was not to be the case. While this text is touted as being for “Biomedical engineers, life sciences researchers, as well as undergraduate and graduate students in Biomedical Engineering, Electrical Engineering, Mathematics, Biology, and Medicine (Academic Press website), this reviewer suggests that the text be mainly considered as a reference text, to be used primarily by those with an adequate mathematical and MATLAB background." --IEEE Review Presents a comprehensive three-step workflow on how to develop a virtual laboratory for experimental and clinical studies From the Back Cover A Comprehensive Physically Based Approach to Modeling in Bioengineering and Life Sciences provides a systematic methodology to the formulation of problems in biomedical engineering and life sciences through the adoption of mathematical models based on fundamental physics principles, such as the conservation of mass, electric charge, momentum, and energy. Readers will learn to translate the mathematical formulation into a numerical algorithm, implementable on a computer, in order to determine an approximate problem solution. A Comprehensive Modeling Approach in Bioengineering and Life Sciences employs computational models as synthesized tools for the investigation, quantification, verification and comparison of different conjectures or scenarios of the behavior of a given compartment of the human body under physiological and pathological conditions. About the Author Dr. Sacco is an applied mathematician whose research and teaching activities span a wide variety of topics including computational biology, semiconductor device modeling and simulation, computational fluid-mechanics and finite element analysis. Dr. Sacco graduated from Politecnico di Milano (Italy) with a BS and MS in electronic engineering (1989), and obtained in 1992 a PhD in applied mathematics from Universita` degli Studi di Milano (Italy). Dr. Sacco was awarded two post-doctoral positions in mathematics from CNR Milano (1992) and Universita` degli Studi di Milano (1994). In 1995 Dr. Sacco joined the faculty at Dipartimento di Matematica Politecnico di Milano (Italy) as assistant professor in Numerical Analysis and later was appointed associate professor in the same institution (2001). Dr. Sacco was included in the "Who's Who in the World 2001" and co-authored with Prof. Alfio Quarteroni and Prof. Fausto Saleri the book "Numerical Mathematics" (1st Ed., Springer New York, 2000). Since 1994 Dr. Sacco has been serving as a referee for more than 20 peer-reviewed international journals ranging from numerical analysis to co