Enzymology at the Membrane Interface: Intramembrane Proteases: Volume 584 (Methods in Enzymology, Volume 584) - Image 1

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Academic Press Enzymology at the Membrane Interface: Intramembrane Proteases: Volume 584 (Methods in Enzymology, Volume 584)

Name: Enzymology at the Membrane Interface: Intramembrane Proteases: Volume 584 (Methods in Enzymology, Volume 584)
Brand: Academic Press
Price: 135.49 GBP
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Description

Enzymology at the Membrane Interface: Intramembrane Proteases, Volume 584, the latest release in the Methods in Enzymology series, covers a subset of enzymes that work in the environment of the biological cell membrane. This field, called interfacial enzymology, involves a special series of experimental approaches for the isolation and study of these enzymes. Review Covers a subset of enzymes that work in the environment of the biological cell membrane, including isolation approaches and study About the Author Michael H. Gelb studied chemistry and biochemistry as an undergraduate at the University of California at Davis. His Ph.D. studies with Stephen G. Sligar at Yale University led to a better understanding of the catalytic mechanism of cytochrome P450. As an American Cancer Society Postdoctoral Fellow in the laboratory of the late Robert H. Abeles at Brandeis University, Gelb studied a variety of mechanism-based inactivators of serine proteases and developed fluorinated ketones as tight-binding inhibitors of several classes of proteases. In 1985 Gelb became a faculty member in the Departments of Chemistry and Biochemistry at the University of Washington. Major breakthroughs in the group include the development of methods to properly analyze the action of enzymes on membrane surfaces, the discovery of protein prenylation (farnesylation and geranylgeranylation) in mammalian cells (together with John A. Glomset), the development of Isotope-Coded Affinity Tags (ICAT reagents) for proteomic applications (together with Ruedi Aebersold), and the development of newborn screening for lysosomal storage diseases by mass spectrometry.

Product Specifications

Brand: Academic Press
Format: hardcover
ASIN: 0128122137
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners
Domain: Amazon UK
Release Date: 06 January 2017
Listed Since: 28 September 2016

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Academic Press Enzymology at the Membrane Interface: Intramembrane Proteases: Volume 584 (Methods in Enzymology, Volume 584)

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