Elsevier Mechanochemical Organic Synthesis

Product Description Mechanochemical Organic Synthesis is a comprehensive reference that not only synthesizes the current literature but also offers practical protocols that industrial and academic scientists can immediately put to use in their daily work. Increasing interest in green chemistry has led to the development of numerous environmentally-friendly methodologies for the synthesis of organic molecules of interest. Amongst the green methodologies drawing attention, mechanochemistry is emerging as a promising method to circumvent the use of toxic solvents and reagents as well as to increase energy efficiency. The development of synthetic strategies that require less, or the minimal, amount of energy to carry out a specific reaction with optimum productivity is of vital importance for large-scale industrial production. Experimental procedures at room temperature are the mildest reaction conditions (essentially required for many temperature-sensitive organic substrates as a key step in multi-step sequence reactions) and are the core of mechanochemical organic synthesis. This green synthetic method is now emerging in a very progressive manner and until now, there is no book that reviews the recent developments in this area. Features cutting-edge research in the field of mechanochemical organic synthesis for more sustainable reactions Integrates advances in green chemistry research into industrial applications and process development Focuses on designing techniques in organic synthesis directed toward mild reaction conditions Includes global coverage of mechanochemical synthetic protocols for the generation of organic compounds Review A comprehensive survey of current literature in this emerging area of green chemistry, which shows promise for circumventing the use of toxic solvents and reagents and increasing energy efficiency From the Back Cover Mechanochemical Organic Synthesis compiles the current literature and also offers practical protocols that industrial and academic scientists can immediately apply in their daily work. With the widespread and increasing interest in green chemistry, numerous environmentally friendly methodologies for the synthesis of organic molecules have been developed. Among the green methodologies that draw attention, mechanochemistry is emerging as a promising method to circumvent the use of toxic solvents and reagents as well as to increase energy efficiency. It is simultaneously of vital importance to efficient, large-scale industrial production to develop synthetic strategies that require a lower amount of energy to carry out a specific reaction with optimum productivity. Experimental procedures at room temperature are the mildest reaction conditions (essentially required for many temperature-sensitive organic substrates as a key step in multistep sequence reactions) and are the core of mechanochemical organic synthesis. Mechanochemical Organic Synthesis offers a comprehensive review of the most recent developments in this area. Key features Includes cutting-edge research in the field of mechanochemical organic synthesis for more sustainable reactions Focuses on designing techniques in organic synthesis directed toward mild reaction conditions Contains global coverage of mechanochemical synthetic protocols for the generation of organic compounds Recapitulates mechanochemical methodologies and reaction monitoring by solid-state ex-situ and in-situ analytical methods Introduces benefits of mechanochemistry to undergraduate education About the Author Dr. Davor Margetić is senior research scientist and acting head of the division of organic chemistry and biochemistry at Ruđer Bošković research Institute in Zagreb, Croatia. He is the head of the laboratory for physical organic chemistry and Professor of physical organic chemistry at Rijeka University.He graduated with a degree in chemical engineering at Zagreb University and continued in the field of organic syntheses with Ms.Sc. and Ph.D.