Molecular Targets in Protein Misfolding and Neurodegenerative Disease: Focus on Tau, Alzheimer's Disease, and Other Tauopathies - Image 1

£51.20

Academic Press Molecular Targets in Protein Misfolding and Neurodegenerative Disease: Focus on Tau, Alzheimer's Disease, and Other Tauopathies

Name: Molecular Targets in Protein Misfolding and Neurodegenerative Disease: Focus on Tau, Alzheimer's Disease, and Other Tauopathies
Brand: Academic Press
Price: 51.2 GBP
Availability: InStock

Diseases & Disorders

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Description

Aimed at "drug discoverers" - i.e. any scientist who is interested in neurodegenerative diseases in general, and in finding disease-modifying treatments in particular - the first edition of Molecular Targets in Protein Misfolding and Neurodegenerative Disease will contain both a detailed, discipline-specific coverage (paragraphs on medicinal chemistry, on clinical and preclinical characterization of compounds in development, on target identification and validation, on genetic factors influencing a pathology, etc.) and a drug discovery-oriented, overall evaluation of each target (validation, druggability, existing leads, etc.). Together these will satisfy the needs of various audiences, including in vitro biologists, pharmacologists, medicinal chemists, etc. * Written to provide a comprehensive coverage of disease-modifying mechanisms and compounds against neurodegenerative diseases* Provides a "drug discovery application oriented perspective, evaluating targets and candidates for their overall therapeutic potential* Provides discipline-specific chapters (medicinal chemistry, target validation, preclinical and clinical development* Provides an overview on a number of molecular mechanisms (e.g. phosphorylation, chaperon refolding, ubiquitination, autophagy, microtubule transportation, protease cleavage, etc.) with relevance for any disease area* Contains a more thorough description of the therapeutic relevance of ~10 specific molecular targets

Product Specifications

Brand: Academic Press
Format: hardcover
ASIN: 0128001860
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Diseases & Disorders
Domain: Amazon UK
Publication Date: 17 October 2014
Listed Since: 02 May 2014

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Academic Press Molecular Targets in Protein Misfolding and Neurodegenerative Disease: Focus on Tau, Alzheimer's Disease, and Other Tauopathies

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