Parkinson's Disease: Molecular and Therapeutic Insights From Model Systems - Image 1

£86.99

Academic Press Parkinson's Disease: Molecular and Therapeutic Insights From Model Systems

Name: Parkinson's Disease: Molecular and Therapeutic Insights From Model Systems
Brand: Academic Press
Price: 87.25 GBP
Availability: InStock

Neurology & Clinical Neurophysiology

Price History & Forecast

Last 81 days • 81 data points (No recent data available)

Historical

Generating forecast...

Price Distribution

Price distribution over 81 days • 1 price levels

Days at Price

Price Analysis

Most common price: £87 (81 days, 100.0%)

Price range: £87 - £87

Price levels: 1 different prices over 81 days

Description

Parkinson’s disease is the second most prevalent neurodegenerative disease and is characterized by the irreversible loss of dopamine neurons. Despite its high prevalence in society and many decades of research, the origin of the pathogenesis and the molecular determinants involved in the disorder has remained elusive. Confounding this issue is the lack of experimental models that completely recapitulate the disease state. The identification of a number of genes thought to play a role in the cell death, and development of both toxin and genetic models to explore the function of the genes both in unaffected and diseased cells are now providing new insights into the molecular basis of the neurodegeneration, as well as therapeutic approaches. In this reference, we will describe the advances and the advantages that various invertebrates, cell culture, rodents, and mammals provide in the identification of the molecular components and mechanisms involved in the cell death, and outline the opportunities that these systems provide in drug discovery. Comprehensive and critical assessment of the utility of various model systems to identify the molecular components and pathways involved in Parkinson’s disease Describes the power of toxin and genetic models to identify novel therapeutic targets and compounds that can be used in PD Current overviews of current status of PD research and discovery from bench-to-bedside Provides novel insights and views on where the future of PD research may lead Provides a powerful teaching tool and template to explore the utility of model systems to identify molecular pathways, molecular targets, and therapeutics that are applicable to a variety of neurological diseases

Product Specifications

Brand: Academic Press
Format: hardcover
ASIN: 0123740282
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Neurology & Clinical Neurophysiology
Domain: Amazon UK
Release Date: 13 December 2007
Listed Since: 08 August 2007

Barcode

No barcode data available

Academic Press Parkinson's Disease: Molecular and Therapeutic Insights From Model Systems

Price History & Forecast

Price Distribution

Price Analysis

Description

Product Specifications

Barcode

Similar Products You Might Like

Mechanisms of Cell Death and Approaches to Neuroprotection/Disease Modification in Parkinson’s Disease (Volume 2) (International Review of Movement Disorders, Volume 2)

Covid-19 and Parkinsonism: Volume 165 (International Review of Neurobiology, Volume 165)

Cortico-Subcortical Dynamics in Parkinson’s Disease (Contemporary Neuroscience)

Dementia with Lewy Body and Parkinson's Disease Patients: Patient, Family, and Clinician Working Together for Better Outcomes

Parkinson Disease, An Issue of Clinics in Geriatric Medicine (Volume 36-1) (The Clinics: Internal Medicine, Volume 36-1)

Parkinson's Disease: Advanced Research and Clinical Care

Behavioral Neurobiology of Huntington's Disease and Parkinson's Disease: 22 (Current Topics in Behavioral Neurosciences, 22)

Macro Roles for MicroRNAs in the Life and Death of Neurons (Research and Perspectives in Neurosciences)

Stereotaxis in Parkinson Syndrome: Clinical-Anatomical Contributions to Its Pathophysiology

Immunotherapy and Biomarkers in Neurodegenerative Disorders (Methods in Pharmacology and Toxicology)

Neurodegenerative Diseases: Unifying Principles

International Neurology: A Clinical Approach

Molecular Pathology of the Prions: 59 (Methods in Molecular Medicine)

Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases

Animal Models of Movement Disorders: Volume I: 61 (Neuromethods, 61)

Neurological Rehabilitation of Parkinson's Disease: 1 (Queen Square Neurological Rehabilitation)

Neural Functions of the Delta-Opioid Receptor

What's Wrong With My Mouse?: Behavioral Phenotyping of Transgenic and Knockout Mice

Oxidative Stress and Neuroprotection: 71 (Journal of Neural Transmission. Supplementa, 71)

The Charnoly Body: A Novel Biomarker of Mitochondrial Bioenergetics

Neurotechnology, Electronics, and Informatics: Revised Selected Papers from Neurotechnix 2013: 13 (Springer Series in Computational Neuroscience, 13)

Stem Cell Technologies in Neuroscience: 126 (Neuromethods, 126)

Deep Learning Approaches for Early Diagnosis of Neurodegenerative Diseases

Spectrums of Amyotrophic Lateral Sclerosis: Heterogeneity, Pathogenesis and Therapeutic Directions