Elsevier Progress in Heterocyclic Chemistry: Volume 21

Progress in Heterocyclic Chemistry (PHC) is an annual review series commissioned by the International Society of Heterocyclic Chemistry (ISHC). Volumes in the series contain both highlights of the previous year’s literature on heterocyclic chemistry and articles on emerging topics of particular interest to heterocyclic chemists. The chapters in Volume 21 constitute a systematic survey of the important original material reported in the literature of heterocyclic chemistry in 2008. Additional articles in this volume review "Biocatalytic approaches to chiral heterocycles" and "Ring-expanded (‘fat’) purines and their nucleoside/nucleotide analogues as broad-spectrum therapeutics." As with previous volumes in the series, Volume 21 apprises academic/industrial chemists and advanced students of developments in heterocyclic chemistry in a convenient format. * Covers the heterocyclic literature published in 2008 * Includes specialized reviews * Features contributions from leading researchers in their fields From the Back Cover Progress in Heterocyclic Chemistry (PHC), is an annual review series commissioned by the International Society of Heterocyclic Chemistry (ISHC). Volumes in the series contain both highlights of the previous years literature on heterocyclic chemistry and articles on new developing topics of particular interest to heterocyclic chemists. The highlight chapters in Volume 21 are all written by leading researchers in their field and these chapters constitute a systematic survey of the important original material reported in the literature of heterocyclic chemistry in 2008. Additional articles in this volume review Biocatalytic approaches to chiral heterocycles and Ring-expanded (fat) purines and their nucleoside/nucleotide analogues as broad-spectrum therapeutics. As with previous volumes in the series, Volume 21 will enable academic and industrial chemists, and advanced students, to keep abreast of developments in heterocyclic chemistry in a convenient way. CONTENTS Biocatalytic approaches to chiral heterocycles (Steven J. Collier, Michael A. K. Vogel, Brian J. Wong and Naga K. Modukuru); Ring-expanded (fat) purines and their nucleoside/nucleotide analogues as broad-spectrum therapeutics (Ramachandra S. Hosmane); Three-membered ring systems (Stephen C. Bergmeier and David J. Lapinsky); Four-membered ring systems (Benito Alcaide and Pedro Almendros); Five-membered ring systems: Thiophenes and Se/Te analogues (Tomasz Janosik and Jan Bergman); pyrroles and benzo analogs (Jonathon S. Russel, Erin T. Pelkey and Sarah J. P. Yoon-Miller); Furans and benzofurans (Xue-Long Hou, Zhen Yang, Kap-Sun Yeung, Henry N.C. Wong); With more than one N atom (Larry Yet); With N and S (Se) atoms (Yong-Jin Wu and Bingwei V. Yang); With O & S (Se, Te) atoms (R. Alan Aitken); With O & N atoms (Stefano Cicchi, Franca M. Cordero, Donatella Giomi); Six-membered ring systems: Pyridine and benzo derivatives (Darrin W. Hopper, Aimee L. Crombie, and Jeremy J. Clemens, and Soojin Kwon); Diazines and benzo derivatives (Amelia Manlove and Michael P. Groziak); Triazines, tetrazines and fused ring polyaza systems (2007) (Dmitry N. Kozhevnikov and Valery N. Kozhevnikov); Triazines, tetrazines and fused ring polyaza systems (2008) (Dmitry N. Kozhevnikov and Valery N. Kozhevnikov); Six-membered ring systems: With O and/or S atoms (John D. Hepworth and B. Mark Heron); Seven-membered rings (Jason A. Smith, Peter P. Molesworth and John H. Ryan); Eight-membered and larger rings (George R. Newkome); Index.| Progress in Heterocyclic Chemistry (PHC), is an annual review series commissioned by the International Society of Heterocyclic Chemistry (ISHC). Volumes in the series contain both highlights of the previous years literature on heterocyclic chemistry and articles on new developing topics of particular interest to heterocyclic chemists. The highlight chapters in Volume 21 are all written by leading researchers in their fi